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American Society of Microbiology ABMM Exam Syllabus Topics:
| Section | Objectives |
|---|---|
| Topic 1: Infectious Disease Principles | - Epidemiology
|
| Topic 2: Laboratory Operations | - Diagnostic workflow
|
| Topic 3: Clinical Microbiology | - Bacteriology
|
| Topic 4: Laboratory Management & Quality Systems | - Quality assurance and quality control
|
American Society of Microbiology ABMM Sample Questions:
1. A clinical microbiology laboratory is evaluating a new rapid diagnostic test for influenza viruses. The test has a high sensitivity but a lower specificity compared to RT-PCR. In a setting with a low prevalence of influenza, the use of this rapid test is MOST likely to result in a high number of:
A) False positive results
B) False negative results
C) True negative results
D) True positive results
2. A patient develops a severe skin infection after a puncture wound sustained while gardening. Culture of the wound exudate grows a Gram-positive, spore-forming bacillus that is anaerobic and produces a potent neurotoxin causing sustained muscle contraction. The MOST likely organism is:
A) Bacillus anthracis
B) Clostridium botulinum
C) Clostridium tetani
D) Clostridium perfringens
3. A microbiology laboratory isolates a Gram-negative rod from a wound infection. The organism is oxidase- negative, ferments lactose on MacConkey agar, and produces indole. The MOST likely identification is:
A) Escherichia coli
B) Klebsiella pneumoniae
C) Serratia marcescens
D) Proteus mirabilis
4. The human virome, the collection of viruses that reside in and on the human body, is increasinglyrecognized for its role in health and disease. Which of the following statements regarding the human virome is MOST accurate?
A) The human virome is largely independent of the host's immune status.
B) The human virome is primarily composed of pathogenic viruses that cause acute infections.
C) The composition of the human virome is relatively stable over time and is not influenced by environmental factors.
D) Bacteriophages, viruses that infect bacteria, are a significant component of the human gut virome.
5. A research laboratory is investigating the mechanisms of antiviral drug resistance. They are studying a herpes simplex virus strain that has developed resistance to acyclovir. The MOST common mechanism of acyclovir resistance in HSV involves mutations in the gene encoding:
A) Viral glycoprotein D
B) Viral protease
C) Viral thymidine kinase
D) Viral DNA polymerase
Solutions:
| Question # 1 Answer: A | Question # 2 Answer: C | Question # 3 Answer: A | Question # 4 Answer: D | Question # 5 Answer: C |








